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A relatively new area of study in the pharmaceutical world is that of peptides. There are some exciting opportunities with peptides when it comes to curing diseases and generally helping humans to live healthier lives. At the center of these studies are research peptides, which play a vital role in helping scientists discover new cures.

What Are Peptides?

Peptides are a chemical compound. They are composed of amino acids, which are small molecules that make up proteins. When two or more amino acids combine into a chain, they form a peptide. Small chains of peptides are often referred to as polypeptides or oligopeptides, depending on their size. If the chain of amino acids continues to grow until there are more than 50 of them, it then becomes classified as a protein.

Peptides have received a lot of attention recently in the scientific community, specifically concerning their impacts on the human body. The research aims to replicate the peptides that exist naturally inside the body and copy some of their effects. This is one reason there are now many peptide-related products on the market, which can provide a variety of health benefits.

My Favorite Peptide BPC-157 (which yes, similar to TB-500, they sound a lot like a Star Wars droid)

BPC-157 is, in a word, a peptide. A peptide is simply a sequence of amino acids. OK, OK, lest you be donning a white lab coat and cringing from that simple description, then I'll be more specific: a peptide is a compound consisting of two or more amino acids linked in a chain, the carboxyl group of each acid being joined to the amino group of the next by a bond like this: OC-NH.

In the case of BPC-157, the peptide is a sequence of amino acids with a molecular formula of 62 carbons, 98 hydrogens, 16 nitrogens, and 22 oxygen atoms (C62-H98-N16-O22).

Should you care to know the nitty-gritty specifics, that comes out to a fifteen amino acid sequence of the following:

L-Valine, glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L-prolylglycyl-L-lysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alanylglycyl-L-leucyl-; glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L-prolylglycyllysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alanylglycyl-L-leucyl-L-valine.

Yep, that's the long, fancy name for BPC-157.

BPC, for reasons you're about to discover, stands for “Body Protecting Compound.” Your body already makes it in your own gastric juices in very small amounts, where it serves to protect and heal your gut. But if you can get the super-concentrated version and get it into your system, it has an extremely high level of biological healing activity just about anywhere you put it

1. BPC-157 and Wound Healing
BPC-157 has been found to have practical applicability in wound therapy, including incisional/excisional wounds, deep burns, diabetic ulcers, and alkali burns. It has been shown to promote healing by resolving vessel constriction, stabilizing the primary platelet plug, and resolving the clot. It has also been found to counteract bleeding disorders produced by amputation and/or anticoagulant application.

Research has shown that BPC-157 can induce nitric oxide generation, which is considered to play a significant role in tissue healing and angiogenesis. This nitric oxide modulation is involved in the healing effect of BPC-157 in different tissue injuries.

BPC-157 has also been found to interact with the nitric oxide system, providing endothelium protection and an angiogenic effect. It has been shown to stimulate the expression of the early growth response 1 gene, which is responsible for cytokine and growth factor generation and early extracellular matrix (collagen) formation.

2. BPC-157 and Gastrointestinal (GI) Health
BPC 157 is originally an anti-ulcer agent, native to and stable in human gastric juice, and is effective across the entire gastrointestinal tract. It has been used in clinical trials for ulcerative colitis and multiple sclerosis, and has shown consistent healing effects on various wounds, including skin, muscle, tendon, ligament, bone, and ulcers in the entire gastrointestinal tract. BPC-157 has been effective in healing various types of fistulas, including external (esophagocutaneous, gastrocutaneous, duodenocutaneous, colocutaneous) and internal (colovesical, rectovaginal) fistulas.

Research has shown that BPC-157 may play a role in maintaining gastrointestinal mucosa integrity, acting as a novel cytoprotection mediator. It has been used in ulcerative colitis trials and has shown potential in counteracting the leaky gut syndrome and free radical scavenging activity in various tissues. It has also been found to counteract various encephalopathies and gastrointestinal and liver lesions induced by non-steroidal anti-inflammatory drugs (NSAIDs). In the context of the brain-gut and gut-brain axes, BPC-157 has demonstrated beneficial effects, including anxiolytic, anticonvulsive, and antidepressant effects.

BPC-157 has also shown potential in resolving major vessel occlusion disturbances, such as ischemia-reperfusion injury following the Pringle maneuver and Budd-Chiari syndrome. It has been suggested that BPC-157 may have a role in endothelium maintenance, which is crucial for the function of the gastrointestinal system

3. BPC-157 and Neurological Health
BPC-157 has been shown to have beneficial effects on neurological disorders. It has been found to counteract various encephalopathies and behavioral disturbances, and it may also have a positive impact on muscle disabilities related to central nervous system disturbances. It has been suggested that BPC-157 therapy might recover many muscle disabilities, including those caused by traumatic brain injury, severe electrolyte disturbances, neurotoxins, neuroleptics, alcohol, serotonin syndrome, and NO-system blockade.

I will typically take 500mcg (micrograms) of BPC-157 orally daily for 2-5 weeks every 4-6 months for a solid healing promotion (especially has helped my knee and gut health). Sometimes I stack TB-500 for a daily 1mg subcutaneously (not orally because does not absorb well) for 2 weeks. Truly works wonders.

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